PEGylated insulin-like growth factor-I affords protection and facilitates recovery of lost functions post-focal ischemia
Abstract Insulin-like growth factor-I (IGF-I) is involved in the maturation and maintenance of neurons, and impaired IGF-I signaling has been shown to play a role in various neurological diseases including stroke. The aim of the present study was to investigate the efficacy of an optimized IGF-I var...
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Autores principales: | Kim Parker, Antonio Berretta, Stefanie Saenger, Manaswini Sivaramakrishnan, Simon A. Shirley, Friedrich Metzger, Andrew N. Clarkson |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2017
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Materias: | |
Acceso en línea: | https://doaj.org/article/9573be34d1cf477683505c56800f4a1c |
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