Sex determining region Y-box 2 (SOX2) amplification is an independent indicator of disease recurrence in sinonasal cancer.

<h4>Objectives</h4>The transcription factor SOX2 (3q26.3-q27) is an embryonic stem cell factor contributing to the induction of pluripotency in terminally differentiated somatic cells. Recently, amplification of the SOX2 gene locus has been described in squamous cell carcinoma (SCC) of d...

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Autores principales: Andreas Schröck, Friederike Göke, Patrick Wagner, Maike Bode, Alina Franzen, Martin Braun, Sebastian Huss, Abbas Agaimy, Stephan Ihrler, Ropika Menon, Robert Kirsten, Glen Kristiansen, Friedrich Bootz, Claudia Lengerke, Sven Perner
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
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Acceso en línea:https://doaj.org/article/95ac521457af477c8b19995ce451261d
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