The bile acid sensor FXR is required for immune-regulatory activities of TLR-9 in intestinal inflammation.
<h4>Background</h4>Toll like receptors (TLRs) sense the intestinal microbiota and regulate the innate immune response. A dysregulation of TLRs function participates into intestinal inflammation. Farnesoid X Receptor (FXR) is a nuclear receptor and bile acid sensor highly expressed in ent...
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| Auteurs principaux: | , , , , , , , , , |
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| Format: | article |
| Langue: | EN |
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Public Library of Science (PLoS)
2013
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| Accès en ligne: | https://doaj.org/article/95ac7d0acba945eca1cf9d528946926d |
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