The bile acid sensor FXR is required for immune-regulatory activities of TLR-9 in intestinal inflammation.

The bile acid sensor FXR is required for immune-regulatory activities of TLR-9 in intestinal inflammation.

<h4>Background</h4>Toll like receptors (TLRs) sense the intestinal microbiota and regulate the innate immune response. A dysregulation of TLRs function participates into intestinal inflammation. Farnesoid X Receptor (FXR) is a nuclear receptor and bile acid sensor highly expressed in ent...

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Autores principales: Barbara Renga, Andrea Mencarelli, Sabrina Cipriani, Claudio D'Amore, Adriana Carino, Angela Bruno, Daniela Francisci, Angela Zampella, Eleonora Distrutti, Stefano Fiorucci
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
Materias:
Medicine
R
Science
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Acceso en línea:https://doaj.org/article/95ac7d0acba945eca1cf9d528946926d
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