T-cell stimuli independently sum to regulate an inherited clonal division fate

Why do populations of highly similar T cells have heterogeneous division destinies in response to antigenic stimulus? Here the authors develop a multiplex-dye assay and a mathematical framework to test clonal heterogeneity and show distinction in division destiny is a result of inter-clonal variabil...

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Auteurs principaux: J. M. Marchingo, G. Prevedello, A. Kan, S. Heinzel, P. D. Hodgkin, K. R. Duffy
Format: article
Langue:EN
Publié: Nature Portfolio 2016
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Accès en ligne:https://doaj.org/article/95b6391d198249d286ba54ffd85a581c
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