NK cells in hypoxic skin mediate a trade-off between wound healing and antibacterial defence

NK cells in hypoxic skin mediate a trade-off between wound healing and antibacterial defence

During wound healing and infection in the skin there is a hypoxic environment involving HIF-1α and NK cells. Here the authors show that NK cells through HIF-1α provide a cross-regulatory balance to provide an adequate antimicrobial defence that can inhibit subsequent wound healing.

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Autores principales: Michal Sobecki, Ewelina Krzywinska, Shunmugam Nagarajan, Annette Audigé, Khanh Huỳnh, Julian Zacharjasz, Julien Debbache, Yann Kerdiles, Dagmar Gotthardt, Norihiko Takeda, Joachim Fandrey, Lukas Sommer, Veronika Sexl, Christian Stockmann
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Science
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Acceso en línea:https://doaj.org/article/95b70bae74314a89afad5e46b3247257
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https://doaj.org/article/95b70bae74314a89afad5e46b3247257

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