The role of response elements organization in transcription factor selectivity: the IFN-β enhanceosome example.

What is the mechanism through which transcription factors (TFs) assemble specifically along the enhancer DNA? The IFN-β enhanceosome provides a good model system: it is small; its components' crystal structures are available; and there are biochemical and cellular data. In the IFN-β enhanceosom...

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Autores principales: Yongping Pan, Ruth Nussinov
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2011
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Acceso en línea:https://doaj.org/article/95d76da77b504d7cbae0c9da211536a4
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