Desymmetrization of meso-bisphosphates using copper catalysis and alkylzirconocene nucleophiles

Copper-catalyzed allylic desymmetrizations are, so far, limited to carbocyclic products with two tertiary stereocenters. Here, the authors report a highly enantioselective Cu-catalyzed desymmetrization of meso carbo- and hetero-cyclic bisphosphates to give products with up to three contiguous stereo...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Reece Jacques, Robert D. C. Pullin, Stephen P. Fletcher
Format: article
Langue:EN
Publié: Nature Portfolio 2019
Sujets:
Q
Accès en ligne:https://doaj.org/article/95ed68147a644b96bbf5abd9358e986a
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!