Desymmetrization of meso-bisphosphates using copper catalysis and alkylzirconocene nucleophiles
Copper-catalyzed allylic desymmetrizations are, so far, limited to carbocyclic products with two tertiary stereocenters. Here, the authors report a highly enantioselective Cu-catalyzed desymmetrization of meso carbo- and hetero-cyclic bisphosphates to give products with up to three contiguous stereo...
Guardado en:
| Autores principales: | , , |
|---|---|
| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
Nature Portfolio
2019
|
| Materias: | |
| Acceso en línea: | https://doaj.org/article/95ed68147a644b96bbf5abd9358e986a |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
| Sumario: | Copper-catalyzed allylic desymmetrizations are, so far, limited to carbocyclic products with two tertiary stereocenters. Here, the authors report a highly enantioselective Cu-catalyzed desymmetrization of meso carbo- and hetero-cyclic bisphosphates to give products with up to three contiguous stereocenters. |
|---|