Microengineered human blood–brain barrier platform for understanding nanoparticle transport mechanisms
Developing an in vitro blood-brain-barrier (BBB) model that reproduces the organ’s complex structure and function is an open challenge. Here the authors present a BBB-on-a-chip that includes endothelial cells, pericytes and a 3D astrocytic network which resembles the morphology and function of astro...
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Main Authors: | Song Ih Ahn, Yoshitaka J. Sei, Hyun-Ji Park, Jinhwan Kim, Yujung Ryu, Jeongmoon J. Choi, Hak-Joon Sung, Tobey J. MacDonald, Allan I. Levey, YongTae Kim |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2020
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Subjects: | |
Online Access: | https://doaj.org/article/95fd2b9d6594462fac69a3cba4e9f50b |
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