Induction of senescence in primary glioblastoma cells by serum and TGFβ
Abstract Glioblastoma is the most common type of adult brain tumour and has a median survival after diagnosis of a little more than a year. Glioblastomas have a high frequency of mutations in the TERT promoter and CDKN2A locus that are expected to render them resistant to both replicative and oncoge...
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Main Authors: | Ritesh Kumar, Alexander Gont, Theodore J. Perkins, Jennifer E. L. Hanson, Ian A. J. Lorimer |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2017
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Subjects: | |
Online Access: | https://doaj.org/article/9600ca8f6ee94a838aaa5c94ff55151b |
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