Glucocorticoid therapy regulates podocyte motility by inhibition of Rac1

Abstract Nephrotic syndrome (NS) occurs when the glomerular filtration barrier becomes excessively permeable leading to massive proteinuria. In childhood NS, immune system dysregulation has been implicated and increasing evidence points to the central role of podocytes in the pathogenesis. Children...

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Bibliographic Details
Main Authors: James C. McCaffrey, Nicholas J. Webb, Toryn M. Poolman, Maryline Fresquet, Cressida Moxey, Leo A. H. Zeef, Ian J. Donaldson, David W. Ray, Rachel Lennon
Format: article
Language:EN
Published: Nature Portfolio 2017
Subjects:
R
Q
Online Access:https://doaj.org/article/964db73076a04303b20e5d2795d70cae
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