Preclinical safety and immunogenicity of Streptococcus pyogenes (Strep A) peptide vaccines

Abstract We have developed two candidate vaccines to protect against multiple strains of Strep A infections. The candidates are combinatorial synthetic peptide vaccines composed of a M protein epitope (J8 or p*17) and a non-M protein epitope (K4S2). To enhance immunogenicity, each peptide is conjuga...

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Autores principales: Simone Reynolds, Manisha Pandey, Jessica Dooley, Ainslie Calcutt, Michael Batzloff, Victoria Ozberk, Jamie-Lee Mills, Michael Good
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/9658d25da71b425b9c969603708be127
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