Preclinical safety and immunogenicity of Streptococcus pyogenes (Strep A) peptide vaccines
Abstract We have developed two candidate vaccines to protect against multiple strains of Strep A infections. The candidates are combinatorial synthetic peptide vaccines composed of a M protein epitope (J8 or p*17) and a non-M protein epitope (K4S2). To enhance immunogenicity, each peptide is conjuga...
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Autores principales: | Simone Reynolds, Manisha Pandey, Jessica Dooley, Ainslie Calcutt, Michael Batzloff, Victoria Ozberk, Jamie-Lee Mills, Michael Good |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/9658d25da71b425b9c969603708be127 |
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