Sympathetic denervation-induced MSC mobilization in distraction osteogenesis associates with inhibition of MSC migration and osteogenesis by norepinephrine/adrb3.
The sympathetic nervous system regulates bone formation and resorption under physiological conditions. However, it is still unclear how the sympathetic nerves affect stem cell migration and differentiation in bone regeneration. Distraction osteogenesis is an ideal model of bone regeneration due to i...
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Main Authors: | Zhaojie Du, Lei Wang, Yinghua Zhao, Jian Cao, Tao Wang, Peng Liu, Yabo Zhang, Xinjie Yang, Xiaobing Cheng, Baolin Liu, Delin Lei |
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Format: | article |
Language: | EN |
Published: |
Public Library of Science (PLoS)
2014
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Online Access: | https://doaj.org/article/9695a951e22a4a0f944b3c38a9af5ca8 |
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