A single-dose live attenuated chimeric vaccine candidate against Zika virus

A single-dose live attenuated chimeric vaccine candidate against Zika virus

Abstract The mosquito-borne Zika virus is an emerging pathogen from the Flavivirus genus for which there are no approved antivirals or vaccines. Using the clinically validated PDK-53 dengue virus vaccine strain as a backbone, we created a chimeric dengue/Zika virus, VacDZ, as a live attenuated vacci...

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Bibliographic Details
Main Authors: Wei-Xin Chin, Regina Ching Hua Lee, Parveen Kaur, Tian Sheng Lew, Thinesshwary Yogarajah, Hao Yuin Kong, Zi-Yun Teo, Cyrill Kafi Salim, Rong-Rong Zhang, Xiao-Feng Li, Sylvie Alonso, Cheng-Feng Qin, Justin Jang Hann Chu
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
Immunologic diseases. Allergy
RC581-607
Neoplasms. Tumors. Oncology. Including cancer and carcinogens
RC254-282
Online Access:https://doaj.org/article/96aefe18a1c54f6fb1c868ba72e76b1d
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https://doaj.org/article/96aefe18a1c54f6fb1c868ba72e76b1d

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