A single-dose live attenuated chimeric vaccine candidate against Zika virus

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A single-dose live attenuated chimeric vaccine candidate against Zika virus

Abstract The mosquito-borne Zika virus is an emerging pathogen from the Flavivirus genus for which there are no approved antivirals or vaccines. Using the clinically validated PDK-53 dengue virus vaccine strain as a backbone, we created a chimeric dengue/Zika virus, VacDZ, as a live attenuated vacci...

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Bibliographic Details
Main Authors:	Wei-Xin Chin, Regina Ching Hua Lee, Parveen Kaur, Tian Sheng Lew, Thinesshwary Yogarajah, Hao Yuin Kong, Zi-Yun Teo, Cyrill Kafi Salim, Rong-Rong Zhang, Xiao-Feng Li, Sylvie Alonso, Cheng-Feng Qin, Justin Jang Hann Chu
Format:	article
Language:	EN
Published:	Nature Portfolio 2021
Subjects:	Immunologic diseases. Allergy RC581-607 Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
Online Access:	https://doaj.org/article/96aefe18a1c54f6fb1c868ba72e76b1d
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