A mixed antagonistic/synergistic miRNA repression model enables accurate predictions of multi-input miRNA sensor activity
MicroRNAs (miRNAs) are important post-transcriptional regulators of gene expression but many quantitative aspects of miRNA biology remain to be elucidated. Based on a library of miRNA sensors, the authors quantify miRNA regulation at single cell level and develop a model to predict miRNA target inte...
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Main Authors: | , , |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2018
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Online Access: | https://doaj.org/article/9713160e9e0b4de492ec105715c1bd3d |
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