Heterotetrameric annexin A2/S100A10 (A2t) is essential for oncogenic human papillomavirus trafficking and capsid disassembly, and protects virions from lysosomal degradation

Abstract Human papillomavirus (HPV) entry into epithelial cells is independent of canonical endocytic pathways. Upon interaction with host cells, HPV establishes infection by traversing through an endocytic pathway that is clathrin- and caveolin-independent, but dependent on the annexin A2/S100A10 h...

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Auteurs principaux: Julia R. Taylor, Daniel J. Fernandez, Shantaé M. Thornton, Joseph G. Skeate, Kim P. Lühen, Diane M. Da Silva, Ralf Langen, W. Martin Kast
Format: article
Langue:EN
Publié: Nature Portfolio 2018
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Accès en ligne:https://doaj.org/article/97141fe03bcf420b9794b641585f6e8a
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