Genomic Instability and Cancer Risk Associated with Erroneous DNA Repair

Many cancers develop as a consequence of genomic instability, which induces genomic rearrangements and nucleotide mutations. Failure to correct DNA damage in DNA repair defective cells, such as in <i>BRCA1</i> and <i>BRCA2</i> mutated backgrounds, is directly associated with...

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Autores principales: Ken-ichi Yoshioka, Rika Kusumoto-Matsuo, Yusuke Matsuno, Masamichi Ishiai
Formato: article
Lenguaje:EN
Publicado: MDPI AG 2021
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Acceso en línea:https://doaj.org/article/971f15a9eace4865990d774e847291e3
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