Structural Basis for the Mechanism of ATP-Dependent Acetone Carboxylation
Abstract Microorganisms use carboxylase enzymes to form new carbon-carbon bonds by introducing carbon dioxide gas (CO2) or its hydrated form, bicarbonate (HCO3 −), into target molecules. Acetone carboxylases (ACs) catalyze the conversion of substrates acetone and HCO3 − to form the product acetoacet...
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Main Authors: | Florence Mus, Brian J. Eilers, Alexander B. Alleman, Burak V. Kabasakal, Jennifer N. Wells, James W. Murray, Boguslaw P. Nocek, Jennifer L. DuBois, John W. Peters |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2017
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Online Access: | https://doaj.org/article/974d0ab5c0a34d4b9a8c4a31370e6562 |
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