Hypoxia inducible factor signaling in breast tumors controls spontaneous tumor dissemination in a site-specific manner
Todd et al employ a PyMT-driven spontaneous murine mammary carcinoma model with mammary-specific deletion of hypoxia inducible factors Hif1α, Hif2α, or von Hippel-Lindau factor to further investigate their role in bone and lung metastasis. They find that HIF signaling in breast tumours controls tumo...
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Auteurs principaux: | , , , , , , , , |
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Format: | article |
Langue: | EN |
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Nature Portfolio
2021
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Accès en ligne: | https://doaj.org/article/975f1c09009840709de77452a7dc73cb |
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