EOMES interacts with RUNX3 and BRG1 to promote innate memory cell formation through epigenetic reprogramming

T box transcription factor Eomesodermin (EOMES) is induced when naïve T cells are converted to innate memory T cells in response to cytokines. Here the authors show that EOMES is recruited to RUNX3-bound enhancers and interacts with BRG1 during innate memory T cell formation.

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Autores principales: Nicolas Istaces, Marion Splittgerber, Viviana Lima Silva, Muriel Nguyen, Séverine Thomas, Aurore Le, Younes Achouri, Emilie Calonne, Matthieu Defrance, François Fuks, Stanislas Goriely, Abdulkader Azouz
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/977399acbe71487ca1c96fd6df9b2092
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