JAK/STAT controls organ size and fate specification by regulating morphogen production and signalling

Morphogens regulate growth and pattern in vertebrate and invertebrate limbs. Here, the authors show that the JAK/STAT pathway promotes the growth of the Hedgehog-producing cell population in theDrosophilawing, thereby allowing the stable localization of the BMP/Dpp organizer.

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Auteurs principaux: Carles Recasens-Alvarez, Ana Ferreira, Marco Milán
Format: article
Langue:EN
Publié: Nature Portfolio 2017
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Accès en ligne:https://doaj.org/article/977a2cedc31b45d0909673b32b8e5572
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