Linear mitochondrial DNA is rapidly degraded by components of the replication machinery

Linear mitochondrial DNA is rapidly degraded by components of the replication machinery

Damaged linearized mtDNA needs to be removed from the cell for mitochondrial genome stability. Here the authors shed light into the identity of the machinery responsible for rapidly degrading linearized DNA, implicating the role of mtDNA replication factors.

Saved in:
Bibliographic Details
Main Authors: Viktoriya Peeva, Daniel Blei, Genevieve Trombly, Sarah Corsi, Maciej J. Szukszto, Pedro Rebelo-Guiomar, Payam A. Gammage, Alexei P. Kudin, Christian Becker, Janine Altmüller, Michal Minczuk, Gábor Zsurka, Wolfram S. Kunz
Format: article
Language:EN
Published: Nature Portfolio 2018
Subjects:
Science
Q
Online Access:https://doaj.org/article/979579d067db4608bae2ab8f5bf93bd8
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doaj.org/article/979579d067db4608bae2ab8f5bf93bd8

Similar Items