The effect of elevated body mass index on ischemic heart disease risk: causal estimates from a Mendelian randomisation approach.
<h4>Background</h4>Adiposity, assessed as elevated body mass index (BMI), is associated with increased risk of ischemic heart disease (IHD); however, whether this is causal is unknown. We tested the hypothesis that positive observational associations between BMI and IHD are causal.<h4...
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Main Authors: | Børge G Nordestgaard, Tom M Palmer, Marianne Benn, Jeppe Zacho, Anne Tybjaerg-Hansen, George Davey Smith, Nicholas J Timpson |
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Format: | article |
Language: | EN |
Published: |
Public Library of Science (PLoS)
2012
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Online Access: | https://doaj.org/article/979c92f2ac1d4f96a089edcea3a8a962 |
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