Exploring the SARS-CoV-2 virus-host-drug interactome for drug repurposing

Information developed to understand the molecular mechanisms of SARS-CoV-2 infection for predicting drug repurposing candidates is time-consuming to integrate and explore. Here, the authors develop an interactive online platform for virus-host interactome exploration and drug (target) identification...

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Autores principales: Sepideh Sadegh, Julian Matschinske, David B. Blumenthal, Gihanna Galindez, Tim Kacprowski, Markus List, Reza Nasirigerdeh, Mhaned Oubounyt, Andreas Pichlmair, Tim Daniel Rose, Marisol Salgado-Albarrán, Julian Späth, Alexey Stukalov, Nina K. Wenke, Kevin Yuan, Josch K. Pauling, Jan Baumbach
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Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/97cfd30dcc8f444386de8cedd10dff72
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spelling oai:doaj.org-article:97cfd30dcc8f444386de8cedd10dff722021-12-02T17:01:22ZExploring the SARS-CoV-2 virus-host-drug interactome for drug repurposing10.1038/s41467-020-17189-22041-1723https://doaj.org/article/97cfd30dcc8f444386de8cedd10dff722020-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-17189-2https://doaj.org/toc/2041-1723Information developed to understand the molecular mechanisms of SARS-CoV-2 infection for predicting drug repurposing candidates is time-consuming to integrate and explore. Here, the authors develop an interactive online platform for virus-host interactome exploration and drug (target) identification.Sepideh SadeghJulian MatschinskeDavid B. BlumenthalGihanna GalindezTim KacprowskiMarkus ListReza NasirigerdehMhaned OubounytAndreas PichlmairTim Daniel RoseMarisol Salgado-AlbarránJulian SpäthAlexey StukalovNina K. WenkeKevin YuanJosch K. PaulingJan BaumbachNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Sepideh Sadegh
Julian Matschinske
David B. Blumenthal
Gihanna Galindez
Tim Kacprowski
Markus List
Reza Nasirigerdeh
Mhaned Oubounyt
Andreas Pichlmair
Tim Daniel Rose
Marisol Salgado-Albarrán
Julian Späth
Alexey Stukalov
Nina K. Wenke
Kevin Yuan
Josch K. Pauling
Jan Baumbach
Exploring the SARS-CoV-2 virus-host-drug interactome for drug repurposing
description Information developed to understand the molecular mechanisms of SARS-CoV-2 infection for predicting drug repurposing candidates is time-consuming to integrate and explore. Here, the authors develop an interactive online platform for virus-host interactome exploration and drug (target) identification.
format article
author Sepideh Sadegh
Julian Matschinske
David B. Blumenthal
Gihanna Galindez
Tim Kacprowski
Markus List
Reza Nasirigerdeh
Mhaned Oubounyt
Andreas Pichlmair
Tim Daniel Rose
Marisol Salgado-Albarrán
Julian Späth
Alexey Stukalov
Nina K. Wenke
Kevin Yuan
Josch K. Pauling
Jan Baumbach
author_facet Sepideh Sadegh
Julian Matschinske
David B. Blumenthal
Gihanna Galindez
Tim Kacprowski
Markus List
Reza Nasirigerdeh
Mhaned Oubounyt
Andreas Pichlmair
Tim Daniel Rose
Marisol Salgado-Albarrán
Julian Späth
Alexey Stukalov
Nina K. Wenke
Kevin Yuan
Josch K. Pauling
Jan Baumbach
author_sort Sepideh Sadegh
title Exploring the SARS-CoV-2 virus-host-drug interactome for drug repurposing
title_short Exploring the SARS-CoV-2 virus-host-drug interactome for drug repurposing
title_full Exploring the SARS-CoV-2 virus-host-drug interactome for drug repurposing
title_fullStr Exploring the SARS-CoV-2 virus-host-drug interactome for drug repurposing
title_full_unstemmed Exploring the SARS-CoV-2 virus-host-drug interactome for drug repurposing
title_sort exploring the sars-cov-2 virus-host-drug interactome for drug repurposing
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/97cfd30dcc8f444386de8cedd10dff72
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