Hotspots of dendritic spine turnover facilitate clustered spine addition and learning and memory

Structural remodeling of dendritic spines is thought to be a mechanism of memory storage. Here, the authors look at how spine turnover and clustering predict future learning and memory performance, and see that a genetically modified mouse with enhanced spine turnover has enhanced learning.

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Bibliographic Details
Main Authors: Adam C. Frank, Shan Huang, Miou Zhou, Amos Gdalyahu, George Kastellakis, Tawnie K. Silva, Elaine Lu, Ximiao Wen, Panayiota Poirazi, Joshua T. Trachtenberg, Alcino J. Silva
Format: article
Language:EN
Published: Nature Portfolio 2018
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Online Access:https://doaj.org/article/9812b8e6055c436ab27e845c4f6d0c38
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