Hotspots of dendritic spine turnover facilitate clustered spine addition and learning and memory

Structural remodeling of dendritic spines is thought to be a mechanism of memory storage. Here, the authors look at how spine turnover and clustering predict future learning and memory performance, and see that a genetically modified mouse with enhanced spine turnover has enhanced learning.

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Autores principales: Adam C. Frank, Shan Huang, Miou Zhou, Amos Gdalyahu, George Kastellakis, Tawnie K. Silva, Elaine Lu, Ximiao Wen, Panayiota Poirazi, Joshua T. Trachtenberg, Alcino J. Silva
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Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/9812b8e6055c436ab27e845c4f6d0c38
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spelling oai:doaj.org-article:9812b8e6055c436ab27e845c4f6d0c382021-12-02T17:31:47ZHotspots of dendritic spine turnover facilitate clustered spine addition and learning and memory10.1038/s41467-017-02751-22041-1723https://doaj.org/article/9812b8e6055c436ab27e845c4f6d0c382018-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-02751-2https://doaj.org/toc/2041-1723Structural remodeling of dendritic spines is thought to be a mechanism of memory storage. Here, the authors look at how spine turnover and clustering predict future learning and memory performance, and see that a genetically modified mouse with enhanced spine turnover has enhanced learning.Adam C. FrankShan HuangMiou ZhouAmos GdalyahuGeorge KastellakisTawnie K. SilvaElaine LuXimiao WenPanayiota PoiraziJoshua T. TrachtenbergAlcino J. SilvaNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Adam C. Frank
Shan Huang
Miou Zhou
Amos Gdalyahu
George Kastellakis
Tawnie K. Silva
Elaine Lu
Ximiao Wen
Panayiota Poirazi
Joshua T. Trachtenberg
Alcino J. Silva
Hotspots of dendritic spine turnover facilitate clustered spine addition and learning and memory
description Structural remodeling of dendritic spines is thought to be a mechanism of memory storage. Here, the authors look at how spine turnover and clustering predict future learning and memory performance, and see that a genetically modified mouse with enhanced spine turnover has enhanced learning.
format article
author Adam C. Frank
Shan Huang
Miou Zhou
Amos Gdalyahu
George Kastellakis
Tawnie K. Silva
Elaine Lu
Ximiao Wen
Panayiota Poirazi
Joshua T. Trachtenberg
Alcino J. Silva
author_facet Adam C. Frank
Shan Huang
Miou Zhou
Amos Gdalyahu
George Kastellakis
Tawnie K. Silva
Elaine Lu
Ximiao Wen
Panayiota Poirazi
Joshua T. Trachtenberg
Alcino J. Silva
author_sort Adam C. Frank
title Hotspots of dendritic spine turnover facilitate clustered spine addition and learning and memory
title_short Hotspots of dendritic spine turnover facilitate clustered spine addition and learning and memory
title_full Hotspots of dendritic spine turnover facilitate clustered spine addition and learning and memory
title_fullStr Hotspots of dendritic spine turnover facilitate clustered spine addition and learning and memory
title_full_unstemmed Hotspots of dendritic spine turnover facilitate clustered spine addition and learning and memory
title_sort hotspots of dendritic spine turnover facilitate clustered spine addition and learning and memory
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/9812b8e6055c436ab27e845c4f6d0c38
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