Hotspots of dendritic spine turnover facilitate clustered spine addition and learning and memory
Structural remodeling of dendritic spines is thought to be a mechanism of memory storage. Here, the authors look at how spine turnover and clustering predict future learning and memory performance, and see that a genetically modified mouse with enhanced spine turnover has enhanced learning.
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Nature Portfolio
2018
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oai:doaj.org-article:9812b8e6055c436ab27e845c4f6d0c382021-12-02T17:31:47ZHotspots of dendritic spine turnover facilitate clustered spine addition and learning and memory10.1038/s41467-017-02751-22041-1723https://doaj.org/article/9812b8e6055c436ab27e845c4f6d0c382018-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-02751-2https://doaj.org/toc/2041-1723Structural remodeling of dendritic spines is thought to be a mechanism of memory storage. Here, the authors look at how spine turnover and clustering predict future learning and memory performance, and see that a genetically modified mouse with enhanced spine turnover has enhanced learning.Adam C. FrankShan HuangMiou ZhouAmos GdalyahuGeorge KastellakisTawnie K. SilvaElaine LuXimiao WenPanayiota PoiraziJoshua T. TrachtenbergAlcino J. SilvaNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-11 (2018) |
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Science Q Adam C. Frank Shan Huang Miou Zhou Amos Gdalyahu George Kastellakis Tawnie K. Silva Elaine Lu Ximiao Wen Panayiota Poirazi Joshua T. Trachtenberg Alcino J. Silva Hotspots of dendritic spine turnover facilitate clustered spine addition and learning and memory |
description |
Structural remodeling of dendritic spines is thought to be a mechanism of memory storage. Here, the authors look at how spine turnover and clustering predict future learning and memory performance, and see that a genetically modified mouse with enhanced spine turnover has enhanced learning. |
format |
article |
author |
Adam C. Frank Shan Huang Miou Zhou Amos Gdalyahu George Kastellakis Tawnie K. Silva Elaine Lu Ximiao Wen Panayiota Poirazi Joshua T. Trachtenberg Alcino J. Silva |
author_facet |
Adam C. Frank Shan Huang Miou Zhou Amos Gdalyahu George Kastellakis Tawnie K. Silva Elaine Lu Ximiao Wen Panayiota Poirazi Joshua T. Trachtenberg Alcino J. Silva |
author_sort |
Adam C. Frank |
title |
Hotspots of dendritic spine turnover facilitate clustered spine addition and learning and memory |
title_short |
Hotspots of dendritic spine turnover facilitate clustered spine addition and learning and memory |
title_full |
Hotspots of dendritic spine turnover facilitate clustered spine addition and learning and memory |
title_fullStr |
Hotspots of dendritic spine turnover facilitate clustered spine addition and learning and memory |
title_full_unstemmed |
Hotspots of dendritic spine turnover facilitate clustered spine addition and learning and memory |
title_sort |
hotspots of dendritic spine turnover facilitate clustered spine addition and learning and memory |
publisher |
Nature Portfolio |
publishDate |
2018 |
url |
https://doaj.org/article/9812b8e6055c436ab27e845c4f6d0c38 |
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