Pericyte-expressed Tie2 controls angiogenesis and vessel maturation

Pericyte-expressed Tie2 controls angiogenesis and vessel maturation

The angiopoietins regulate vascular maturation, angiogenesis and lymphangiogenesis via their Tie receptors that were long believed to be endothelium-specific. Here the authors show that angiopoietins activate and control pericyte function through pericyte-expressed Tie2 triggering of Calpain, Akt an...

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Main Authors: Martin Teichert, Laura Milde, Annegret Holm, Laura Stanicek, Nicolas Gengenbacher, Soniya Savant, Tina Ruckdeschel, Zulfiyya Hasanov, Kshitij Srivastava, Junhao Hu, Stella Hertel, Arne Bartol, Katharina Schlereth, Hellmut G. Augustin
Format: article
Language:EN
Published: Nature Portfolio 2017
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Science
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Online Access:https://doaj.org/article/981a987e79e44cc08ee1f10a3f710c40
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https://doaj.org/article/981a987e79e44cc08ee1f10a3f710c40

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