Haploid Genetic Screen Reveals a Profound and Direct Dependence on Cholesterol for Hantavirus Membrane Fusion

ABSTRACT Hantaviruses cause hemorrhagic fever with renal syndrome (HFRS) in the Old World and a highly fatal hantavirus cardiopulmonary syndrome (HCPS) in the New World. No vaccines or antiviral therapies are currently available to prevent or treat hantavirus disease, and gaps in our understanding o...

Full description

Saved in:
Bibliographic Details
Main Authors: Lara M. Kleinfelter, Rohit K. Jangra, Lucas T. Jae, Andrew S. Herbert, Eva Mittler, Katie M. Stiles, Ariel S. Wirchnianski, Margaret Kielian, Thijn R. Brummelkamp, John M. Dye, Kartik Chandran
Format: article
Language:EN
Published: American Society for Microbiology 2015
Subjects:
Online Access:https://doaj.org/article/983bfed9990349deb89d2c2be0fb9944
Tags: Add Tag
No Tags, Be the first to tag this record!