A high-throughput screen identifies a new natural product with broad-spectrum antibacterial activity.

Due to the inexorable invasion of our hospitals and communities by drug-resistant bacteria, there is a pressing need for novel antibacterial agents. Here we report the development of a sensitive and robust but low-tech and inexpensive high-throughput metabolic screen for novel antibiotics. This scre...

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Autores principales: Patrick Ymele-Leki, Shugeng Cao, Jared Sharp, Kathleen G Lambert, Alexander J McAdam, Robert N Husson, Giselle Tamayo, Jon Clardy, Paula I Watnick
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
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Acceso en línea:https://doaj.org/article/9843c48a4d704992ac1a54554b9a3aa7
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