A high-throughput screen identifies a new natural product with broad-spectrum antibacterial activity.
Due to the inexorable invasion of our hospitals and communities by drug-resistant bacteria, there is a pressing need for novel antibacterial agents. Here we report the development of a sensitive and robust but low-tech and inexpensive high-throughput metabolic screen for novel antibiotics. This scre...
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Main Authors: | Patrick Ymele-Leki, Shugeng Cao, Jared Sharp, Kathleen G Lambert, Alexander J McAdam, Robert N Husson, Giselle Tamayo, Jon Clardy, Paula I Watnick |
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Format: | article |
Language: | EN |
Published: |
Public Library of Science (PLoS)
2012
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Online Access: | https://doaj.org/article/9843c48a4d704992ac1a54554b9a3aa7 |
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