Distinctive roles of tumor necrosis factor receptor type 1 and type 2 in a mouse disc degeneration model

Background: Elevated tumor necrosis factor alpha (TNF-α) expression is correlated with the progression of intervertebral disc degeneration (IVDD). Progranulin binding to tumor necrosis factor receptor (TNFR) and its derivative Atsttrin are effective for treating inflammatory arthritis. We hypothesiz...

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Bibliographic Details
Main Authors: Shanzheng Wang, Guodong Sun, Pan Fan, Lei Huang, Yaofei Chen, Changhong Chen
Format: article
Language:EN
Published: Elsevier 2021
Subjects:
Online Access:https://doaj.org/article/9857b067f1c54e2a897f7f6453973e34
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