Hypothesis: Entrapment of lipoprotein particles in the brain causes Alzheimer’s disease

We present for consideration a hypothesis that impaired movement of lipoprotein particles in the extracellular space in the brain in ageing is central to and causes all the key pathophysiological features of Alzheimer’s disease (AD). The role of lipoprotein particles is to transport cholesterol fro...

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Autores principales: Delphine Boche, James AR Nicoll
Formato: article
Lenguaje:EN
Publicado: University of Münster / Open Journals System 2021
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Acceso en línea:https://doaj.org/article/9890ce4721294cc38b8e35d6308bff1a
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