The therapeutic significance of mutational signatures from DNA repair deficiency in cancer
Targeting DNA repair-deficient tumors is one of the most promising therapeutic strategies in cancer research; however, accurately predicting which tumors will respond can be a challenge. Here the authors present a review of the current state of knowledge in DNA repair deficiency across human cancers...
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Auteurs principaux: | , , , , |
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Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2018
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Accès en ligne: | https://doaj.org/article/989e83e9fb614cad8639f2b928fc7330 |
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