Genomic architecture and prediction of censored time-to-event phenotypes with a Bayesian genome-wide analysis

Few genome-wide association studies have explored the genetic architecture of age-of-onset for traits and diseases. Here, the authors develop a Bayesian approach to improve prediction in timing-related phenotypes and perform age-of-onset analyses across complex traits in the UK Biobank.

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Autores principales: Sven E. Ojavee, Athanasios Kousathanas, Daniel Trejo Banos, Etienne J. Orliac, Marion Patxot, Kristi Läll, Reedik Mägi, Krista Fischer, Zoltan Kutalik, Matthew R. Robinson
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/98babe5c070d44148cee67c1123085fa
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