Generation of reconstituted hemato-lymphoid murine embryos by placental transplantation into embryos lacking HSCs

Abstract In order to increase the contribution of donor HSC cells, irradiation and DNA alkylating agents have been commonly used as experimental methods to eliminate HSCs for adult mice. But a technique of HSC deletion for mouse embryo for increase contribution of donor cells has not been published....

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Autores principales: Hyojung Jeon, Keigo Asano, Arata Wakimoto, Kaushalya Kulathunga, Mai Thi Nhu Tran, Megumi Nakamura, Tomomasa Yokomizo, Michito Hamada, Satoru Takahashi
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/98c72039521d4ef6b1e5ffbb80d0d82b
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