Heparanase inhibition preserves the endothelial glycocalyx in lung grafts and improves lung preservation and transplant outcomes

Abstract The endothelial glycocalyx (eGC) is considered a key regulator of several mechanisms that prevent vascular injury and disease. Degradation of this macromolecular layer may be associated with post-transplant graft dysfunction. In this study, we aimed to demonstrate the benefits of eGC protec...

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Autores principales: Kentaro Noda, Brian J. Philips, Mark E. Snyder, Julie A. Phillippi, Mara Sullivan, Donna B. Stolz, Xi Ren, James D. Luketich, Pablo G. Sanchez
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/98cf30a0f9ce40b5b2955bce29674e74
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