Heparanase inhibition preserves the endothelial glycocalyx in lung grafts and improves lung preservation and transplant outcomes
Abstract The endothelial glycocalyx (eGC) is considered a key regulator of several mechanisms that prevent vascular injury and disease. Degradation of this macromolecular layer may be associated with post-transplant graft dysfunction. In this study, we aimed to demonstrate the benefits of eGC protec...
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Autores principales: | Kentaro Noda, Brian J. Philips, Mark E. Snyder, Julie A. Phillippi, Mara Sullivan, Donna B. Stolz, Xi Ren, James D. Luketich, Pablo G. Sanchez |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/98cf30a0f9ce40b5b2955bce29674e74 |
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