ANTIHYPOXIC PROPERTIES OF THE DRY EXTRACT FROM SERRATULA CENTAUROIDES

The influence of the dry extract from Serratula centauroides roots on the resistance to the hemic, hystotoxic and hypercapnic hypoxias was investigated in the experiments on white rats. It was established that the course administration of the remedy in the doses of50,100,150 mg/kg increases the resi...

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Main Authors:	V. .. Sviridov, Ya. G. Razuvaeva, L. N. Shantanova
Format:	article
Language:	RU
Published:	Scientific Сentre for Family Health and Human Reproduction Problems 2014
Subjects:	serratula centauroides hypoxic states antihypoxic action Science Q
Online Access:	https://doaj.org/article/98d4001f9d0b41408af1c79d1999a73c
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id	oai:doaj.org-article:98d4001f9d0b41408af1c79d1999a73c
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spelling	oai:doaj.org-article:98d4001f9d0b41408af1c79d1999a73c2021-11-23T06:14:31ZANTIHYPOXIC PROPERTIES OF THE DRY EXTRACT FROM SERRATULA CENTAUROIDES2541-94202587-9596https://doaj.org/article/98d4001f9d0b41408af1c79d1999a73c2014-11-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/1841https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596The influence of the dry extract from Serratula centauroides roots on the resistance to the hemic, hystotoxic and hypercapnic hypoxias was investigated in the experiments on white rats. It was established that the course administration of the remedy in the doses of50,100,150 mg/kg increases the resistance of the experimental animals to hypoxias of different genesis. S. centauroides in the dose of 150 mg/kg has the most pronounced antihypoxic activity, increasing the lifespan of the animals with hemic and normobaric hypoxia on average by 60 % (p < 0,001) and and with histotoxic hypoxia - by 50 % (p < 0,001).V. .. SviridovYa. G. RazuvaevaL. N. ShantanovaScientific Сentre for Family Health and Human Reproduction Problemsarticleserratula centauroidesserratula centauroideshypoxic statesantihypoxic actionScienceQRUActa Biomedica Scientifica, Vol 0, Iss 6, Pp 77-79 (2014)
institution	DOAJ
collection	DOAJ
language	RU
topic	serratula centauroides serratula centauroides hypoxic states antihypoxic action Science Q
spellingShingle	serratula centauroides serratula centauroides hypoxic states antihypoxic action Science Q V. .. Sviridov Ya. G. Razuvaeva L. N. Shantanova ANTIHYPOXIC PROPERTIES OF THE DRY EXTRACT FROM SERRATULA CENTAUROIDES
description	The influence of the dry extract from Serratula centauroides roots on the resistance to the hemic, hystotoxic and hypercapnic hypoxias was investigated in the experiments on white rats. It was established that the course administration of the remedy in the doses of50,100,150 mg/kg increases the resistance of the experimental animals to hypoxias of different genesis. S. centauroides in the dose of 150 mg/kg has the most pronounced antihypoxic activity, increasing the lifespan of the animals with hemic and normobaric hypoxia on average by 60 % (p < 0,001) and and with histotoxic hypoxia - by 50 % (p < 0,001).
format	article
author	V. .. Sviridov Ya. G. Razuvaeva L. N. Shantanova
author_facet	V. .. Sviridov Ya. G. Razuvaeva L. N. Shantanova
author_sort	V. .. Sviridov
title	ANTIHYPOXIC PROPERTIES OF THE DRY EXTRACT FROM SERRATULA CENTAUROIDES
title_short	ANTIHYPOXIC PROPERTIES OF THE DRY EXTRACT FROM SERRATULA CENTAUROIDES
title_full	ANTIHYPOXIC PROPERTIES OF THE DRY EXTRACT FROM SERRATULA CENTAUROIDES
title_fullStr	ANTIHYPOXIC PROPERTIES OF THE DRY EXTRACT FROM SERRATULA CENTAUROIDES
title_full_unstemmed	ANTIHYPOXIC PROPERTIES OF THE DRY EXTRACT FROM SERRATULA CENTAUROIDES
title_sort	antihypoxic properties of the dry extract from serratula centauroides
publisher	Scientific Сentre for Family Health and Human Reproduction Problems
publishDate	2014
url	https://doaj.org/article/98d4001f9d0b41408af1c79d1999a73c
work_keys_str_mv	AT vsviridov antihypoxicpropertiesofthedryextractfromserratulacentauroides AT yagrazuvaeva antihypoxicpropertiesofthedryextractfromserratulacentauroides AT lnshantanova antihypoxicpropertiesofthedryextractfromserratulacentauroides
_version_	1718417084650618880

ANTIHYPOXIC PROPERTIES OF THE DRY EXTRACT FROM SERRATULA CENTAUROIDES

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