Defining the nature of thermal intermediate in 3 state folding proteins: apoflavodoxin, a study case.

The early stages of the thermal unfolding of apoflavodoxin have been determined by using atomistic multi microsecond-scale molecular dynamics (MD) simulations complemented with a variety of experimental techniques. Results strongly suggest that the intermediate is reached very early in the thermal u...

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Bibliographic Details
Main Authors: Rebeca García-Fandiño, Pau Bernadó, Sara Ayuso-Tejedor, Javier Sancho, Modesto Orozco
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2012
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Online Access:https://doaj.org/article/98e2b5b6f34847b29722140132b82605
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