N-Glycosylation can selectively block or foster different receptor–ligand binding modes

Abstract While DNA encodes protein structure, glycans provide a complementary layer of information to protein function. As a prime example of the significance of glycans, the ability of the cell surface receptor CD44 to bind its ligand, hyaluronan, is modulated by N-glycosylation. However, the detai...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Joni Vuorio, Jana Škerlová, Milan Fábry, Václav Veverka, Ilpo Vattulainen, Pavlína Řezáčová, Hector Martinez-Seara
Format: article
Langue:EN
Publié: Nature Portfolio 2021
Sujets:
R
Q
Accès en ligne:https://doaj.org/article/990ff85791054a3e937ff2ae25de0092
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!