Adventitious Virus Detection in Cells by High-Throughput Sequencing of Newly Synthesized RNAs: Unambiguous Differentiation of Cell Infection from Carryover of Viral Nucleic Acids

ABSTRACT The use of high-throughput sequencing (HTS) to identify viruses in biologicals differs from current molecular approaches, since its use enables an unbiased approach to detection without the need to design specific primers to preamplify target sequences. Its broad range of detection and anal...

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Bibliographic Details
Main Authors: Justine Cheval, Erika Muth, Gaëlle Gonzalez, Muriel Coulpier, Pascale Beurdeley, Stéphane Cruveiller, Marc Eloit
Format: article
Language:EN
Published: American Society for Microbiology 2019
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Online Access:https://doaj.org/article/9917511c9eb944cb851a21b7b3b67334
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