The Gonium pectorale genome demonstrates co-option of cell cycle regulation during the evolution of multicellularity

The Gonium pectorale genome demonstrates co-option of cell cycle regulation during the evolution of multicellularity

The undifferentiated Gonium pectorale represents the initial transition to multicellularity. Here, Bradley Olson, Erik Hanschen and colleagues describe the genome of Gonium pectorale, demonstrating that co-option of the retinoblastoma cell cycle regulatory pathway was a key genetic change in the evo...

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Main Authors: Erik R. Hanschen, Tara N. Marriage, Patrick J. Ferris, Takashi Hamaji, Atsushi Toyoda, Asao Fujiyama, Rafik Neme, Hideki Noguchi, Yohei Minakuchi, Masahiro Suzuki, Hiroko Kawai-Toyooka, David R. Smith, Halle Sparks, Jaden Anderson, Robert Bakarić, Victor Luria, Amir Karger, Marc W. Kirschner, Pierre M. Durand, Richard E. Michod, Hisayoshi Nozaki, Bradley J. S. C. Olson
Format: article
Language:EN
Published: Nature Portfolio 2016
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Science
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Online Access:https://doaj.org/article/992e5a79e84e4946ab532b4d08cda741
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Summary:The undifferentiated Gonium pectorale represents the initial transition to multicellularity. Here, Bradley Olson, Erik Hanschen and colleagues describe the genome of Gonium pectorale, demonstrating that co-option of the retinoblastoma cell cycle regulatory pathway was a key genetic change in the evolution of multicellularity.

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