Multivariate genomic scan implicates novel loci and haem metabolism in human ageing

Ageing phenotypes are of great interest but are difficult to study genetically, partly due to the sample sizes required. Here, the authors present a multivariate framework to combine GWAS summary statistics and increase statistical power, identifying additional loci enriched for aging.

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Auteurs principaux: Paul R. H. J. Timmers, James F. Wilson, Peter K. Joshi, Joris Deelen
Format: article
Langue:EN
Publié: Nature Portfolio 2020
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Accès en ligne:https://doaj.org/article/9965e11c40b1450baa676536e95faa0a
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