Multivariate genomic scan implicates novel loci and haem metabolism in human ageing

Ageing phenotypes are of great interest but are difficult to study genetically, partly due to the sample sizes required. Here, the authors present a multivariate framework to combine GWAS summary statistics and increase statistical power, identifying additional loci enriched for aging.

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Bibliographic Details
Main Authors: Paul R. H. J. Timmers, James F. Wilson, Peter K. Joshi, Joris Deelen
Format: article
Language:EN
Published: Nature Portfolio 2020
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Online Access:https://doaj.org/article/9965e11c40b1450baa676536e95faa0a
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