Targets of complement-fixing antibodies in protective immunity against malaria in children

Antibodies against Plasmodium falciparum merozoites that fix complement can inhibit blood-stage replication. Here, Reiling et al. show that complement-fixing antibodies strongly correlate with protective immunity in children, identify the merozoite targets, and predict antigen combinations that shou...

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Autores principales: Linda Reiling, Michelle J. Boyle, Michael T. White, Danny W. Wilson, Gaoqian Feng, Rupert Weaver, D. Herbert Opi, Kristina E. M. Persson, Jack S. Richards, Peter M. Siba, Freya J. I. Fowkes, Eizo Takashima, Takafumi Tsuboi, Ivo Mueller, James G. Beeson
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/997676a5fefb4ce79727443868c02da7
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