Urate transporter inhibitor lesinurad is a selective peroxisome proliferator-activated receptor gamma modulator (sPPARγM) in vitro

Abstract Gout is the most common arthritic disease in human but was long neglected and therapeutic options are not satisfying. However, with the recent approval of the urate transporter inhibitor lesinurad, gout treatment has experienced a major innovation. Here we show that lesinurad possesses cons...

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Autores principales: Pascal Heitel, Leonie Gellrich, Jan Heering, Tamara Goebel, Astrid Kahnt, Ewgenij Proschak, Manfred Schubert-Zsilavecz, Daniel Merk
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/99894e9ac49c488b912c6cbbe9902276
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