In vivo analysis of onset and progression of retinal degeneration in the Nr2e3 rd7/rd7 mouse model of enhanced S-cone sensitivity syndrome

Abstract The photoreceptor-specific nuclear receptor Nr2e3 is not expressed in Nr2e3 rd7/rd7 mice, a mouse model of the recessively inherited retinal degeneration enhanced S-cone sensitivity syndrome (ESCS). We characterized in detail C57BL/6J Nr2e3 rd7/rd7 mice in vivo by fundus photography, optica...

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Auteurs principaux: Giulia Venturini, Despina Kokona, Beatrice L. Steiner, Emanuele G. Bulla, Joel Jovanovic, Martin S. Zinkernagel, Pascal Escher
Format: article
Langue:EN
Publié: Nature Portfolio 2021
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R
Q
Accès en ligne:https://doaj.org/article/998c07516489425aa2d964b03d8eb876
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