Hepatocellular Carcinoma Cells Are Protected From Immunolysis by Mesenchymal Stromal Cells Through Indoleamine 2,3 Dioxygenase

B7 family proteins serve as checkpoint molecules that protect tumors from T cell mediated lysis. Tryptophan degrading enzymes indoleamine 2,3 dioxygenase (IDO) and tryptophan 2,3 dioxygenase (TDO) also induce T cell immune tolerance. However, little is known about the relative contribution of B7 mol...

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Auteurs principaux: Raghavan Chinnadurai, Amanda Paige Porter, Mihir Patel, Ariel Joy Lipat, Mathews H. Forsberg, Devi Rajan, Peiman Hematti, Christian M. Capitini, Charles Bruker
Format: article
Langue:EN
Publié: Frontiers Media S.A. 2021
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Accès en ligne:https://doaj.org/article/99ee81a0e482403ab182d77d66ad8b4a
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